Acumen Pharmaceuticals

Acumen Pharmaceuticals, Inc. discovers and develops medicines and diagnostics for Alzheimer's disease. The company was founded by William L. Klein, Grant A. Krafft and Caleb Finch in 1996 and is headquartered in Charlottesville, VA.

Earnings data Q2 2021

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Acumen Pharmaceuticals reports robust Q4 earnings, ACU193 progress promising

Acumen Pharmaceuticals showcased strong financials and progress with ACU193 in their Q4 2022 earnings call. While facing challenges related to dosing strategies and commercial implications, the company is well-positioned to capitalize on opportunities for further development and market success.

Acumen Pharmaceuticals reports robust Q1 performance and advances Alzheimer's program

Acumen Pharmaceuticals demonstrates strong financial stability and progress in their Alzheimer's program.
Strategic focus on target engagement and dose selection enhances the clinical development pathway for ACU193.
Challenges lie in managing trial scenarios, but opportunities exist in data insights and regulatory interactions.

Acumen Pharmaceuticals reports positive Phase I results and solid financial standing

Acumen Pharmaceuticals showcased promising results for ACU193 in early Alzheimer's treatment and maintained a strong financial position with ample runway for future activities.
While facing challenges in dose selection and fundraising needs, the company has opportunities to advance drug development and explore innovative dosing methods.

Acumen Pharmaceuticals reports Q3 loss but advances Alzheimer's treatment

Acumen Pharmaceuticals showcased positive advancements in ACU193 with promising CSF biomarker results, despite reporting a loss from operations in Q3.
The company's strong financial position, highlighted by $282.7 million in cash and a new credit facility, supports ongoing research and development efforts.
Addressing operational challenges and seizing opportunities in refining treatment approaches and study timelines are crucial for Acumen Pharmaceuticals' future success.

Acumen Pharmaceuticals reports positive Phase I results for Alzheimer's treatment

Acumen Pharmaceuticals showcased progress in sabirnetug development, facing challenges in study design and dosing strategies while aiming to capitalize on therapeutic opportunities for Alzheimer's treatment.

Acumen Pharmaceuticals reports Q1 loss, progresses ALTITUDE study

Acumen Pharmaceuticals faces challenges in R&D expenses and logistical integration but shows strength in collaborations and enrollment progress.
Opportunities lie in diversification through new studies and potential incorporation of formulations into ongoing trials.
Overall, the company's financials and strategic focus indicate progress and commitment to advancing drug development.

Acumen Pharmaceuticals advances Alzheimer's treatment with strong financial backing

Acumen Pharmaceuticals is on track with the development of sabirnetug, backed by strong financials and a clear strategy to address Alzheimer's disease. While facing enrollment and market challenges, the company's upcoming R&D Day could unlock new opportunities for growth and innovation.

Acumen Pharmaceuticals reports progress in Alzheimer's treatment development and financial stability

Acumen Pharmaceuticals is making significant progress in its clinical efforts for sabirnetug, with faster-than-expected enrollment in the Phase II study.
The company's financial stability, highlighted by $259 million in cash and marketable securities, supports ongoing research and development initiatives.
Challenges in managing R&D expenses and addressing analyst inquiries underscore the complexities and opportunities in advancing Alzheimer's treatments.

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Acumen Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company, which discovers and develops medicines and diagnostics for Alzheimer's disease. The company was founded by William L. Klein, Grant A. Krafft, and Caleb Finch in 1996 and is headquartered in Charlottesville, VA.

Acumen Pharmaceuticals, Inc. (ABOS) Q4 2023 Earnings Call Transcript

CHARLOTTESVILLE, Va., March 26, 2024 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS) (“Acumen” or the “Company”), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers (AβOs) for the treatment of Alzheimer's disease (AD), today reported financial results for the full year ended December 31, 2023 and provided a business update.

Acumen Pharmaceuticals Reports Financial Results for the Year Ended December 31, 2023 and Business Highlights

Here is how Acumen Pharmaceuticals, Inc. (ABOS) and Ayr Wellness Inc. (AYRWF) have performed compared to their sector so far this year.

Is Acumen Pharmaceuticals (ABOS) Outperforming Other Medical Stocks This Year?

CHARLOTTESVILLE, Va., March 19, 2024 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS) (“Acumen” or the “Company”), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, today announced that the Company will report fourth quarter and year-end 2023 financial results on Tuesday, March 26, 2024. The Company will host a conference call and live audio webcast at 8:00 a.m. ET to provide a business and financial update.

Acumen Pharmaceuticals to Report Fourth Quarter and Year-End 2023 Financial Results on March 26, 2024

CHARLOTTESVILLE, Va., March 12, 2024 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today that management will participate in a fireside chat as part of the Stifel 2024 CNS Days on Tuesday, March 19, 2024, at 12:00 p.m. ET.

Acumen Pharmaceuticals to Participate in the Stifel 2024 CNS Days

- Cerebrospinal fluid (CSF) biomarker results are highly supportive of sabirnetug's downstream pharmacological effects in the brain in early AD

Acumen Pharmaceuticals Presents Sabirnetug (ACU193) Fluid Biomarker and Target Engagement Analyses from Phase 1 INTERCEPT-AD Study in Early Alzheimer's at the AD/PD™ 2024 Annual Meeting

Here is how Acumen Pharmaceuticals, Inc. (ABOS) and Akoya Biosciences (AKYA) have performed compared to their sector so far this year.

Has Acumen Pharmaceuticals (ABOS) Outpaced Other Medical Stocks This Year?

-   Oral presentation to explore drug effect of sabirnetug (ACU193) on key cerebrospinal fluid biomarkers in early AD

Acumen Pharmaceuticals to Present Sabirnetug (ACU193) Fluid Biomarker and Target Engagement Analyses from Phase 1 INTERCEPT-AD Study in Early Alzheimer's at the AD/PD™ 2024 Annual Meeting

CHARLOTTESVILLE, Va., Feb. 01, 2024 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today the appointment of James Doherty, Ph.D., as President and Chief Development Officer, effective February 1, 2024, reporting to Daniel O'Connell, Chief Executive Officer. Dr. Doherty's responsibilities will include oversight of clinical and non-clinical development, chemistry, manufacturing & controls and regulatory functions.

Acumen Pharmaceuticals Appoints Dr. James Doherty as President and Chief Development Officer

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CHARLOTTESVILLE, Va., Jan. 04, 2024 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today that management will present at the 42nd Annual J.P.

Acumen Pharmaceuticals to Present at the 42nd Annual J.P. Morgan Healthcare Conference

Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS ) Q3 2023 Earnings Conference Call November 13, 2023 08:00 AM ET Company Participants Alex Braun - Head-IR Daniel O'Connell - CEO Eric Siemers - Chief Medical Officer Matt Zuga - CFO & Chief Business Officer Conference Call Participants Thomas Shrader - BTIG Pete Stavropoulos - Cantor Fitzgerald Colin Bristow - UBS Presentation Operator Good day, ladies and gentlemen. Thank you for standing by.

Acumen Pharmaceuticals, Inc. (ABOS) Q3 2023 Earnings Call Transcript

CHARLOTTESVILLE, Va., Nov. 13, 2023 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS) (“Acumen” or the “Company”), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers (“AβOs”) for the treatment of Alzheimer's disease (“AD”), today announced that it has entered into a senior secured loan and security agreement (the “Loan Agreement”) with K2 HealthVentures, a healthcare-focused specialty finance company.

Acumen Pharmaceuticals Secures $50.0 Million Credit Facility with K2 HealthVentures

CHARLOTTESVILLE, Va., Nov. 13, 2023 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS) (“Acumen” or the “Company”), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers (AβOs) for the treatment of Alzheimer's disease (AD), today reported financial results for the third quarter of 2023 and provided a business update.

Acumen Pharmaceuticals Reports Third Quarter 2023 Financial Results and Business Highlights

CHARLOTTESVILLE, VA. and INDIANAPOLIS, IN., Nov. 06, 2023 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS) (“Acumen” or the “Company”), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, today announced that the Company will report third quarter financial results on Monday, Nov. 13, 2023. The Company will host a conference call and live audio webcast at 8:00 a.m. ET to provide a business and financial update.

Acumen Pharmaceuticals to Report Third Quarter Financial Results on November 13, 2023

Expect to initiate Phase 1 development in mid-2024 to compare pharmacokinetics of subcutaneous form to intravenous form of ACU193 Expect to initiate Phase 1 development in mid-2024 to compare pharmacokinetics of subcutaneous form to intravenous form of ACU193

Acumen Pharmaceuticals, Inc. and Halozyme Enter Global Collaboration and License Agreement to Develop Subcutaneous Formulation of ACU193 with ENHANZE® Technology

CHARLOTTESVILLE, Va., Nov. 02, 2023 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today that management will participate in a fireside chat at the UBS Biopharma Conference on Thursday, Nov. 9, 2023 at 10:00 a.m. ET. The live webcast may be accessed under the Investors tab on www.acumenpharm.com and will be archived for 90 days.

Acumen Pharmaceuticals to Participate in the UBS Biopharma Conference

CHARLOTTESVILLE, Va. and INDIANAPOLIS, Oct. 04, 2023 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets soluble amyloid beta oligomers (AβOs) for the treatment of Alzheimer's disease (AD), today announced that it will present deeper insights and new exploratory findings from its Phase 1 INTERCEPT-AD trial evaluating ACU193, the first clinical-stage AβO-directed antibody therapy for early AD, at the 16th Annual Clinical Trials on Alzheimer's Disease (CTAD) conference taking place in Boston and online from October 24-27, 2023. INTERCEPT-AD was selected to be featured in a symposium on Friday, October 27, and data from exploratory analyses of the Phase 1 trial will also be shared in two in-person and two virtual poster presentations.

Acumen Pharmaceuticals to Present Deeper Insights from First-in-Human Phase 1 Study of ACU193 for Early Alzheimer's During Symposium at the 16th Annual Clinical Trials on Alzheimer's Disease (CTAD)

Acumen Pharmaceuticals' ACU193 shows promise as a potential treatment for early-stage Alzheimer's Disease, targeting amyloid beta oligomers with a more favorable safety profile. Q2 earnings show increased operating expenses and a net loss expansion, but a recent capital injection extends the cash runway and lowers the threat of near-term dilution. Market sentiment is cautious, but the Phase 1 results and financial stability suggest a potential buying opportunity for risk-tolerant investors.

Navigating Acumen's Alzheimer's Risk And Reward

Acumen Pharmaceuticals is developing a monoclonal antibody, ACU193, that targets Amyloid beta oligomers (AβOs) in Alzheimer's disease. AβOs are small, soluble aggregates of amyloid-beta peptides that are believed to be more toxic to neurons than amyloid plaques. ACU193 demonstrated proof-of-mechanism in a phase 1 trial, showing significant reduction in amyloid plaques and a favorable safety profile. A phase 2/3 trial is planned for next year.

Acumen Pharmaceuticals: Novel Alzheimer's Molecule With Positive Early Data

CHARLOTTESVILLE, Va. and CARMEL, Ind., Sept. 19, 2023 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today that management will participate in a panel discussion at the Cantor Global Healthcare Conference on Tuesday, Sept. 26, 2023 at 9:20 a.m. ET. The live webcast may be accessed under the Investors tab on www.acumenpharm.com and will be archived for 90 days.

Acumen Pharmaceuticals to Participate in the Cantor Global Healthcare Conference

Here is how Acumen Pharmaceuticals, Inc. (ABOS) and Haemonetics (HAE) have performed compared to their sector so far this year.

Are Medical Stocks Lagging Acumen Pharmaceuticals (ABOS) This Year?

CHARLOTTESVILLE, Va. and CARMEL, Ind., Sept. 06, 2023 (GLOBE NEWSWIRE) -- Acumen Pharmaceuticals, Inc. (NASDAQ: ABOS), a clinical-stage biopharmaceutical company developing a novel therapeutic that targets toxic soluble amyloid beta oligomers for the treatment of Alzheimer's disease, announced today that management will present at the H.C. Wainwright 25th Annual Global Investment Conference on Wednesday, Sept. 13, 2023 at 10:30 a.m. ET. The live webcast may be accessed under the Investors tab on www.acumenpharm.com and will be archived for 90 days.

Acumen Pharmaceuticals to Participate in the H.C. Wainwright Annual Global Investment Conference

Acumen Pharmaceuticals, Inc. (NASDAQ:ABOS ) Q2 2023 Earnings Conference Call August 8, 2023 8:00 AM ET Company Participants Alex Braun - Head-Investor Relations Dan O'Connell - Chief Executive Officer Eric Siemers - Chief Medical Officer Matt Zuga - Chief Financial Officer & Chief Business Officer Conference Call Participants Colin Bristow - UBS Paul Matteis - Stifel Tom Shrader - BTIG Pete Stavropoulos - Cantor Fitzgerald Charlie Yang - Bank of America Operator Thank you for standing by, and welcome to the Acumen Pharmaceuticals Second Quarter 2023 Update Call. At this time, all participants are in a listen-only mode.

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