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Denali Therapeutics (DNLI) Stock Forecast & Price Target

Denali Therapeutics (DNLI) Analyst Ratings

Based on 20 analyst ratings
Strong Buy
Strong Buy 60%
Buy 40%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Denali Therapeutics Inc. is poised for significant growth, with key milestones such as an imminent BLA accelerated approval filing projected to capture a substantial market share in the Hunter's disease sector starting in 2026. The company is strategically enhancing its operational efficiency through in-house manufacturing of enzymes, antibodies, and OTVs, which supports the launch of 1-2 planned INDs each year through 2027 while maintaining operational expenditures that remain manageable, tracking below previous estimates. Furthermore, clinical updates highlighting favorable patient outcomes, including improvements in neurocognitive functions and liver volume normalization, reinforce the therapeutic promise of its lead products and position Denali favorably against existing treatments in neurodegeneration.

Bears say

Denali Therapeutics Inc faces significant challenges that may negatively impact its stock outlook, primarily due to potential failures or delays in the development and commercialization of its product candidates. Recent developments, such as the discontinuation of the III dose cohort for Elaprase, raise concerns about the real-world durability of its therapies, which could hinder broader adoption and delay revenue generation. Additionally, the company reported a substantial net loss of $114.8 million, compounded by market uncertainties and competitive pressures that could adversely affect sales projections for its key products.

Denali Therapeutics (DNLI) has been analyzed by 20 analysts, with a consensus rating of Strong Buy. 60% of analysts recommend a Strong Buy, 40% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Denali Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Denali Therapeutics (DNLI) Forecast

Analysts have given Denali Therapeutics (DNLI) a Strong Buy based on their latest research and market trends.

According to 20 analysts, Denali Therapeutics (DNLI) has a Strong Buy consensus rating as of Jul 24, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $35.40, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $35.40, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Denali Therapeutics (DNLI)


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