
Ionis Pharma (IONS) Stock Forecast & Price Target
Ionis Pharma (IONS) Analyst Ratings
Bulls say
Ionis Pharmaceuticals has demonstrated a strong financial outlook, raising its 2025 revenue guidance to $875-900 million, up from the previously expected $825-850 million, which reflects robust product performances and improved uptake of its recent product launches, including Tryngolza. The company reported impressive revenue figures, with Tryngolza achieving $32 million in the third quarter of 2025, surpassing consensus estimates, alongside steady contributions from partnered programs like Spinraza and Wainua. Furthermore, Ionis continues to strengthen its pipeline through successful regulatory actions, including plans for an sNDA submission for olezarsen, enhancing dosing flexibility and convenience for both healthcare providers and patients.
Bears say
Ionis Pharmaceuticals is facing a negative outlook primarily due to its significant financial losses and a lack of anticipated profitability over the next several years, with a GAAP net loss of $129 million in the latest quarter. The company reported a decrease in cash and equivalents, ending 3Q25 with $2.24 billion, indicating potential liquidity concerns amidst increased operational costs and competitive pressures in the market. Furthermore, multiple risks threaten Ionis's financial stability, including erosion of Spinraza's market share, slower market uptake of its products, and possible regulatory delays which could hinder their late-stage candidates, contributing to uncertainty in their growth trajectory.
This aggregate rating is based on analysts' research of Ionis Pharma and is not a guaranteed prediction by Public.com or investment advice.
Ionis Pharma (IONS) Analyst Forecast & Price Prediction
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