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Prelude Therapeutics (PRLD) Stock Forecast & Price Target

Prelude Therapeutics (PRLD) Analyst Ratings

Based on 3 analyst ratings
Buy
Strong Buy 33%
Buy 67%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Prelude Therapeutics Inc. demonstrates a positive outlook primarily due to the promising clinical development of its pipeline candidates, particularly PRT3789, a first-in-class SMARCA2/BRM protein degrader. The company's phase 2 candidate has shown significant efficacy in treating SMARCA4-mutated cancers, supported by dose-dependent increases in exposure and prolonged degradation of SMARCA2 in patient samples. As the selected 500mg QW dosage for PRT3789 is associated with higher efficacy and reduced pharmacodynamic measures in tumors, it suggests a strong potential for successful outcomes in ongoing trials.

Bears say

Prelude Therapeutics faces significant risks that contribute to a negative outlook, particularly surrounding the clinical development of its candidates, namely PRT3789. There is a potential for negative clinical results, delays in advancing candidates into registrational programs, and obstacles in obtaining regulatory approvals, which may hinder the company's progress in a competitive landscape. Additionally, the decision to pause the development of PRT3789 in favor of focusing on PRT7732 highlights strategic uncertainties and introduces long-term dilution risks, further exacerbating financial concerns.

Prelude Therapeutics (PRLD) has been analyzed by 3 analysts, with a consensus rating of Buy. 33% of analysts recommend a Strong Buy, 67% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Prelude Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Prelude Therapeutics (PRLD) Forecast

Analysts have given Prelude Therapeutics (PRLD) a Buy based on their latest research and market trends.

According to 3 analysts, Prelude Therapeutics (PRLD) has a Buy consensus rating as of Dec 15, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $4, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $4, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Prelude Therapeutics (PRLD)


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