
Prelude Therapeutics (PRLD) Stock Forecast & Price Target
Prelude Therapeutics (PRLD) Analyst Ratings
Bulls say
Prelude Therapeutics Inc. demonstrates a positive outlook primarily due to the promising clinical development of its pipeline candidates, particularly PRT3789, a first-in-class SMARCA2/BRM protein degrader. The company's phase 2 candidate has shown significant efficacy in treating SMARCA4-mutated cancers, supported by dose-dependent increases in exposure and prolonged degradation of SMARCA2 in patient samples. As the selected 500mg QW dosage for PRT3789 is associated with higher efficacy and reduced pharmacodynamic measures in tumors, it suggests a strong potential for successful outcomes in ongoing trials.
Bears say
Prelude Therapeutics faces significant risks that contribute to a negative outlook, particularly surrounding the clinical development of its candidates, namely PRT3789. There is a potential for negative clinical results, delays in advancing candidates into registrational programs, and obstacles in obtaining regulatory approvals, which may hinder the company's progress in a competitive landscape. Additionally, the decision to pause the development of PRT3789 in favor of focusing on PRT7732 highlights strategic uncertainties and introduces long-term dilution risks, further exacerbating financial concerns.
This aggregate rating is based on analysts' research of Prelude Therapeutics and is not a guaranteed prediction by Public.com or investment advice.
Prelude Therapeutics (PRLD) Analyst Forecast & Price Prediction
Start investing in Prelude Therapeutics (PRLD)
Order type
Buy in
Order amount
Est. shares
0 shares