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SEPN
Volume: 877.88K

Septerna Inc (SEPN) Stock Forecast & Price Target

Septerna Inc (SEPN) Analyst Ratings

Based on 8 analyst ratings
Strong Buy
Strong Buy 63%
Buy 38%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Septerna is poised for success due to its strong pipeline in three highly lucrative therapeutic areas, backed by a proven Native Complex Platform. Their lead candidate, SEP-631, has the potential to become a best-in-class treatment for mast cell-driven diseases, while their TSHR NAM candidate and GLP-1R/GIPR/GCGR agonist candidate bring further diversity and potential revenue streams. With conservative assumptions applied, our DCF-based valuation yields a price objective of $40 per share, indicating a strong upside potential for investors. However, risks to achieving this price target include potential delays in development, setbacks in clinical trials, and partnership risks.

Bears say

Septerna is facing significant challenges with their pipeline, as their Phase 2 CSU trial with MRGPRX2 NAM, SEP-631, was jeopardized by competitor data, causing them to re-evaluate their plans. Furthermore, their Ph 2 AD study with EVO756 is expected to miss in 3Q26 due to a presumed lack of efficacy. While there is potential for SEP-479 to achieve success in the rare disease market, there are also significant risks that could impact the company's development and commercialization timelines. With a conservative financial outlook and potential dilution risk, Septerna's stock could face challenges in the coming years.

Septerna Inc (SEPN) has been analyzed by 8 analysts, with a consensus rating of Strong Buy. 63% of analysts recommend a Strong Buy, 38% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Septerna Inc and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Septerna Inc (SEPN) Forecast

Analysts have given Septerna Inc (SEPN) a Strong Buy based on their latest research and market trends.

According to 8 analysts, Septerna Inc (SEPN) has a Strong Buy consensus rating as of Aug 14, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $47.75, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $47.75, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Septerna Inc (SEPN)

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