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Septerna Inc (SEPN) Stock Forecast & Price Target

Septerna Inc (SEPN) Analyst Ratings

Based on 4 analyst ratings
Buy
Strong Buy 25%
Buy 50%
Hold 25%
Sell 0%
Strong Sell 0%

Bulls say

Septerna Inc. demonstrates a strong positive outlook due to its proprietary Native Complex Platform, which has the potential to significantly enhance the development of G protein-coupled receptor (GPCR) therapies, particularly in areas of endocrinology, immunology, and metabolic disease. The company’s management expresses confidence in its ability to execute Phase 1 trials more efficiently with its candidate SEP-786, backed by improved preclinical testing and a potentially superior pharmacokinetic profile compared to previous iterations. Additionally, promising results from TPTx rat models indicate that SEP-479 effectively restores calcium/phosphate balance, showcasing the therapeutic potential of its current pipeline.

Bears say

Septerna Inc. is experiencing challenges that contribute to a negative outlook on its stock, particularly related to its clinical-stage pipeline, which has yet to deliver commercially viable products despite its innovative approach to G protein-coupled receptor (GPCR) drug discovery. The company is heavily reliant on the success of its proprietary Native Complex Platform, which is still unproven in generating revenue, raising concerns about the long-term sustainability of its financial health. Additionally, the therapeutic areas targeted, such as endocrinology and immunology, face significant competition and regulatory hurdles, which may impede the development timelines and market entry of its product candidates.

Septerna Inc (SEPN) has been analyzed by 4 analysts, with a consensus rating of Buy. 25% of analysts recommend a Strong Buy, 50% recommend Buy, 25% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Septerna Inc and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Septerna Inc (SEPN) Forecast

Analysts have given Septerna Inc (SEPN) a Buy based on their latest research and market trends.

According to 4 analysts, Septerna Inc (SEPN) has a Buy consensus rating as of Oct 29, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $26.75, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $26.75, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Septerna Inc (SEPN)


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