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SYRE

SYRE Stock Forecast & Price Target

SYRE Analyst Ratings

Based on 13 analyst ratings
Strong Buy
Strong Buy 62%
Buy 38%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Spyre Therapeutics is a clinical-stage biopharmaceutical company focused on developing innovative therapies for inflammatory bowel disease (IBD) and other immune-mediated diseases. With a portfolio of extended half-life antibodies targeting key inflammatory pathways, the company is positioned to potentially improve treatment outcomes for patients with IBD. The recent positive data for its lead candidate, SPY003, and the potential for differentiated combination therapies with its other candidates suggest a strong future outlook for Spyre, with significant value potential for investors. However, as an early-stage biopharma company, Spyre carries typical risks associated with drug development, including clinical trial outcomes and regulatory hurdles.

Bears say

Spyre Therapeutics is making progress in its development of extended half-life antibodies targeting key inflammatory biomarkers for the treatment of IBD, with its recent SPY003 data demonstrating proof-of-concept and comparable efficacy and safety to current standard of care treatments. However, uncertainties surrounding regulatory requirements and the recent fall short of data for SPY072 in rheumatoid arthritis may hinder the company's ability to gain market traction and could lead to delays and increased discount rates for its pipeline programs. As such, the analyst has a negative outlook on the stock with a revised price target of $123.

SYRE has been analyzed by 13 analysts, with a consensus rating of Strong Buy. 62% of analysts recommend a Strong Buy, 38% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Spyre Therapeutics Inc and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Spyre Therapeutics Inc (SYRE) Forecast

Analysts have given SYRE a Strong Buy based on their latest research and market trends.

According to 13 analysts, SYRE has a Strong Buy consensus rating as of Sep 28, 2026. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $107.38, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $107.38, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Spyre Therapeutics Inc (SYRE)


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